Saccharomyces cerevisiae as a chemo-selective bio-catalyst in reduction of (3-(3-nitrophenyl)aziridin-2-yl)-1-phenyl-methanone, pyruvate ester, and 2-acetyl-Ȗ-butyrolactone

Sogol Motallebi Tala-Tapeh, Nosrat O. Mahmoodi, Ali Vaziri


In  a  green  procedure  (3-(3-nitrophenyl)aziridin-2-yl)-1-phenyl-methanone,  pyruvate  ester,  and  2-
acetyl-Ȗ-butyrolactone  were  reduced  to  corresponding  (3-(3-nitrophenyl)aziridin-2-yl)(phenyl)methanol,  2-
hydroxy  propionic  acid  ethyl  ester  and  dihydro-3-(1-hydroxyethyl)furan-2(3H)-one  using  saccharomyces
cerevisiae at ambient temperature. The structure of products was confirmed by IR and 1H NMR spectra.


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